Researchers have developed a new system that allows you to edit genes in mammalian mammalian cells based on long-range light.
Far red is located between red and infrared (710-800 nm), although it is visible, but because of the low energy photons does not participate in photosynthesis. Recently, the team from the Institute of Biomedical Sciences of China found that it can be easier to change the structure of the genome in the organs.
Using the SPLIT-CAS9 system in combination with light-red light LED lighting, scientists were able to effectively edit individual sections of genes located in mammalian cells, including a non-homologous connection of the ends and homologous recovery. With the help of the new method, the team successfully changed the oncogen in the mouse tumor.
The study also showed that a new system can be used for programmable editing of the tissue genome in biological and biomedical context with high accuracy.
Recall that in March we developed technology that allows
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